Working with Green Arrow, Batman chases after the Djinn Uthool. When Uthool suddenly disappears, it turns out that Uthool has possessed Batman where he defeats Booster Gold, Wonder Woman, and Cyborg in his plot to have the Hall of Justice's core temperature break the Earth's mantle. Upon Uthool transforming Batman into a bat monster, Superman ends up fighting Uthool in order to get him out of Batman.
Superman, Batman, and Wonder Woman pursue the remaining Djinn Abnegazar, Rath, and Nyorlath where they plan to reopen Calythos' fissure. The drain Superman and Wonder Woman's powers upon saying their name. John Constantine arrives to help them as Green Arrow, Plastic Man, and Swamp Thing also arrive to fight the three Djinn. Afterwards, Black Adam breaks free from his Earthly imprisonment to fight the heroes as Batman arrives with Shazam as the Justice League fights Black Adam and the remaining Djinn.
After a brief team up with Batman and Big Barda in their battle against the Parademons, Superman is transported to a planet orbiting a red sun by Steppenwolf. This is part of Steppenwolf's plan to kill Superman and become a legend. Now with his powers slowly depleting, Superman must defeat Steppenwolf and get back to Earth. As this is happening, Batman and Big Barda head to Darkseid's fortress on Apokolips in order to find information on where Superman is transported to.
When the Justice League Watchtower is invaded by Toyman and his army of....toys, Cyborg, Wonder Woman, Superman, and Batman are turned into players in a twisted version of a fighting game, and now Cyborg will need all of his gaming skills to get out of this one.
Superman has been infected by the "Repulse", who was revealed as Lex Luthor, and has now become the new Repulse. As Wonder Woman and Hawkman try to find a way to save him, Superman must remove those nanobots from his body by sending them into a black hole before he gets pulled into it as well.
After defeating Harley Quinn, Batman and Zatanna encounter Brother Night who used his dark magic to control the Batmobile and kidnapping Zatanna. With the help of Etrigan the Demon, Batman must save her, stop the Batmobile, and defeat Brother Night.
Felix Faust steals Zatanna's hat in order to free a massive demon and get his youth back. While Batman and Etrigan face off against the demon, Zatanna uses every trick in her arsenal to get her hat back from Felix Faust.
Lex Luthor and Circe invade Themyscira, home of the Amazons, to obtain a staff that leads to the Fallen Realm and an artifact of the Greek Gods. With help from Superman and Batman, Wonder Woman must find a way to stop those villains before it's too late.
Lobo stole the rings from the Red Lanterns and pits Atrocitus, Zilius Zox and the rest of the Red Lanterns against Batman, Superman, and Wonder Woman in order to get a score. After Lobo unlocked the Spider Gauntlet's power, the Justice League and the Red Lanterns must team up to defeat him.
Mr. Freeze flies on his aircraft to freeze the entire Gotham City using Killer Frost as his power source. While Batman deals with Mr. Freeze, Firestorm will have to save Killer Frost and develops a crush on her at the same time.
Cain the Caretaker tells the audience a Halloween story about the House of Mystery, where Batman, Zatanna, Constantine, and Doctor Fate are turned into 10-year-olds by Klarion the Witch Boy. Now, the 10-year-old Justice League must find a way to defeat Klarion, turn them back to normal, and escape the House of Mystery before it disappears by midnight.
While Superman, Batman, Cyborg, and Vixen try to stop Brainiac, Plastic Man sneaks into Brainiac's spaceship to destroy the shrink ray and save the world in order to prove that he is a worthy superhero.
The Atom shrinks Superman down to microscopic size so that he can enter the Bottled City of Kandor but when Brainiac breaks into the Fortress of Solitude, defeats Cyborg, and reclaims the bottle, Atom must try to stop Brainiac on his own.
As Superman gives Blue Beetle, Firestorm, and Stargirl a tour of the Fortress of Solitude, they run afoul with General Zod, Faora, and an unidentified Kryptonian villain who are accidentally freed from the Phantom Zone. Now with Superman trapped inside, the three teen heroes must work together to stop the Kryptonian villains.
While the Justice League attempts to protect the United Nations from Grodd's gorilla army, Mr. Mxyptlk pops up from the fifth dimension and thinks it would be great fun to put each of the Super Heroes' brains into another hero's body.
When Firestorm's alter-ego, Dr. Martin Stein tells Ronnie, that Dr. Stein and Mr. Terrific were room mates in college, old rivalries resurface with Dr Stein insisting his "Smart Cubes" were superior to Mr. Terrifc's "T-Spheres". But when super-villain, the "Calculator" attacks, it's takes both technologies and both heroes,to bring him to justice.
When Gorilla Grodd takes control over Titano, the giant ape, the only person who seems to be able to override his control is the medical worker who nursed him as a chimp. She's now known as Harley Quinn.