Col. MacKenzie is shocked to learn his friend was killed assaulting a business woman by her brother in their house. As the Colonel gets to know her, the relationship turns to love but he soon learns the brother may tear them apart as well.
The Virginian is sent to check out the Bonham ranch which is up for sale. Once there he finds himself caught in the fight between the brothers Foster and Jack who own the ranch and involved in the murder of a woman he once knew.
On the way home Tate finds himself in the middle of hunting party where the prey is a young Shawnee boy. Tate discovering the boy is deaf-mute takes him to jail after learning he is wanted for murder but finds he becomes the boy's lawyer.
In nearly abandoned Spencer Flats, Trampas is held by Della and Annie Spencer, who accuse him of being outlaw Deke Slaughter, though their handyman is not so convinced. Then the real Slaughter rides into the town, claiming to be a sheriff.
The Virginian is sent to look at buying an Angus herd from a widow. He arrives to find that someone is causing problems for her on the ranch ever since her husband died months earlier. Her son believes it is a neighbor but she disagrees.
MacKenzie meets a girl in a daze who is thrown off her horse. He takes her to the cabin of the hermit Muley. Initially, the girl doesn't react to them but she slowly recovers some memory. A stranger arrives saying she is wanted for murder.
Tate helps ramrod a small ranch when the owner leaves to buy new breeding stock. However, the owner's plan to fence his pasture is met with strong resistance by a neighbor stopping Tate plus a surprise arrivals adds to the problems.
During the Ghost Dance movement a troop of soldiers visits Col MacKenzie to warn him and the ranchers. Parker as does MacKenzie recognizes Sgt. Mulcahy as a long thought dead Lt. Baxter from MacKenzie's Lancer regiment in India.
The Virginian on a business trip to Montana finds himself in an area where protection is provided by an ex-outlaw to several towns. All is well until he is forced to kill one of the enforcers. That puts his life on the line with no backup.
After being mauled by a cunning wolf he has been tracking, and then robbed of his possessions by a stranger, MacKenzie is taken in by a homesteader and her son. The wolf, however, is still at large and MacKenzie is determined to kill him.
After stopping in the town of Jump-Up to see an old girlfriend, Tate is cheated in a card game by a gambler, and then framed by town boss John Timothy Driscoll and his son for killing the man, and forced into a hard labor camp.