Most Popular Epidemic Movies and TV Shows
- Movies or TV
- IMDb Rating
- Instant Watch Options
- In Theaters
- On TV
- Release Year
1. 28 Days Later... (2002)
R | 113 min | Drama, Horror, Sci-Fi
Four weeks after a mysterious, incurable virus spreads throughout the UK, a handful of survivors try to find sanctuary.
Votes: 351,059 | Gross: $45.06M
2. V for Vendetta (2005)
R | 132 min | Action, Drama, Sci-Fi
In a future British tyranny, a shadowy freedom fighter, known only by the alias of "V", plots to overthrow it with the help of a young woman.
Votes: 967,263 | Gross: $70.51M
3. Apocalypto (2006)
R | 139 min | Action, Adventure, Drama
As the Mayan kingdom faces its decline, a young man is taken on a perilous journey to a world ruled by fear and oppression.
Votes: 274,127 | Gross: $50.87M
4. Contagion (2011)
PG-13 | 106 min | Action, Drama, Thriller
Healthcare professionals, government officials and everyday people find themselves in the midst of a worldwide epidemic as the CDC works to find a cure.
Votes: 203,751 | Gross: $75.66M
5. World War Z (2013)
PG-13 | 116 min | Action, Adventure, Horror
Former United Nations employee Gerry Lane traverses the world in a race against time to stop the Zombie pandemic that is toppling armies and governments, and threatening to destroy humanity itself.
Votes: 563,159 | Gross: $202.36M
6. The Stand (1994)
Not Rated | 361 min | Adventure, Drama, Fantasy
After a deadly plague kills most of the world's population, the remaining survivors split into two groups - one led by a benevolent elder and the other by a maleficent being - to face each other in a final battle between good and evil.
7. I Am Legend (2007)
PG-13 | 101 min | Drama, Sci-Fi, Thriller
Years after a plague kills most of humanity and transforms the rest into monsters, the sole survivor in New York City struggles valiantly to find a cure.
Votes: 644,375 | Gross: $256.39M
8. Children of Men (2006)
R | 109 min | Drama, Sci-Fi, Thriller
In 2027, in a chaotic world in which women have become somehow infertile, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea.
Votes: 435,622 | Gross: $35.55M
9. 12 Monkeys (1995)
R | 129 min | Mystery, Sci-Fi, Thriller
In a future world devastated by disease, a convict is sent back in time to gather information about the man-made virus that wiped out most of the human population on the planet.
Votes: 546,374 | Gross: $57.14M
11. The Aviator (2004)
PG-13 | 170 min | Biography, Drama
A biopic depicting the early years of legendary Director and aviator Howard Hughes' career from the late 1920s to the mid 1940s.
Votes: 312,937 | Gross: $102.61M
14. The Return of the Living Dead (1985)
R | 91 min | Comedy, Horror, Sci-Fi
When two bumbling employees at a medical supply warehouse accidentally release a deadly gas into the air, the vapors cause the dead to rise again as zombies.
Votes: 50,384 | Gross: $14.24M
15. 12 Monkeys (2015–2018)
TV-14 | 42 min | Adventure, Drama, Mystery
Follows the journey of a time traveler from the post-apocalyptic future who appears in present day on a mission to locate and eradicate the source of a deadly plague that will nearly destroy the human race.
16. Pride and Prejudice and Zombies (2016)
PG-13 | 108 min | Action, Comedy, Fantasy
Five sisters in 19th century England must cope with the pressures to marry while protecting themselves from a growing population of zombies.
Votes: 47,387 | Gross: $10.91M
17. The Island (2005)
PG-13 | 136 min | Action, Sci-Fi, Thriller
A man living in a futuristic sterile colony begins to question his circumscribed existence when his friend is chosen to go to the Island, the last uncontaminated place on earth.
Votes: 290,443 | Gross: $35.82M
18. War for the Planet of the Apes (2017)
PG-13 | 140 min | Action, Adventure, Drama
After the apes suffer unimaginable losses, Caesar wrestles with his darker instincts and begins his own mythic quest to avenge his kind.
Votes: 208,108 | Gross: $146.88M
20. Dawn of the Dead (1978)
Unrated | 127 min | Horror, Thriller
Following an ever-growing epidemic of zombies that have risen from the dead, two Philadelphia S.W.A.T. team members, a traffic reporter, and his television executive girlfriend seek refuge in a secluded shopping mall.
Votes: 105,032 | Gross: $5.10M
21. The Darkest Minds (2018)
PG-13 | 104 min | Action, Adventure, Drama
Imprisoned by an adult world that now fears everyone under 18, a group of teens form a resistance group to fight back and reclaim control of their future.
Votes: 24,001 | Gross: $12.70M
22. Maze Runner: The Scorch Trials (2015)
PG-13 | 131 min | Action, Sci-Fi, Thriller
After having escaped the Maze, the Gladers now face a new set of challenges on the open roads of a desolate landscape filled with unimaginable obstacles.
Votes: 205,485 | Gross: $81.70M
23. Rabid (1977)
R | 91 min | Horror, Sci-Fi
A young woman develops a taste for human blood after experimental plastic surgery, and her victims turn into blood-thirsty zombies, leading into a city-wide epidemic.
24. Cabin Fever (2002)
R | 93 min | Horror
Five college graduates rent a cabin in the woods and begin to fall victim to a horrifying flesh-eating virus, which attracts the unwanted attention of the homicidal locals.
Votes: 70,853 | Gross: $21.16M
25. REC (2007)
R | 78 min | Action, Horror, Mystery
A television reporter and cameraman follow emergency workers into a dark apartment building and are quickly locked inside with something terrifying.
26. The Happening (2008)
R | 91 min | Drama, Mystery, Sci-Fi
A science teacher, his wife, and a young girl struggle to survive a plague that causes those infected to commit suicide.
Votes: 188,234 | Gross: $64.51M
27. Rise of the Planet of the Apes (2011)
PG-13 | 105 min | Action, Drama, Sci-Fi
A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.
Votes: 477,999 | Gross: $176.76M
28. Utopia (I) (2013–2014)
TV-MA | 50 min | Drama, Mystery, Sci-Fi
After a group of people, who meet online, discover a bizarre graphic novel which seems to hold mysterious answers, they find themselves being tracked down by a merciless organization known merely as 'The Network'.
29. Doomsday (2008)
R | 105 min | Action, Sci-Fi, Thriller
A futuristic action thriller where a team of people work to prevent a disaster threatening the future of the human race.
Votes: 69,843 | Gross: $10.96M
30. Land of the Dead (2005)
R | 93 min | Horror, Sci-Fi, Thriller
The living dead have taken over the world, and the last humans live in a walled city to protect themselves as they come to grips with the situation.
Votes: 88,065 | Gross: $20.70M
31. Maggie (I) (2015)
PG-13 | 95 min | Drama, Horror
A teenage girl in the Midwest becomes infected by an outbreak of a disease that slowly turns the infected into cannibalistic zombies. During her transformation, her loving father stays by her side.
Votes: 39,482 | Gross: $0.19M
32. Daybreakers (2009)
R | 98 min | Action, Fantasy, Horror
In the year 2019, a plague has transformed almost every human into vampires. Faced with a dwindling blood supply, the fractured dominant race plots their survival; meanwhile, a researcher works with a covert band of vamps on a way to save humankind.
Votes: 117,900 | Gross: $30.10M
33. The Crazies (2010)
R | 101 min | Horror, Thriller
After a strange and insecure plane crash, an unusual toxic virus enters a quaint farming town. A young couple are quarantined, but they fight for survival along with help from a couple of people.
Votes: 105,772 | Gross: $39.12M
34. The Falling (2014)
Not Rated | 102 min | Drama, Mystery, Thriller
It's 1969 at a strict English girls' school where charismatic Abbie and intense and troubled Lydia are best friends. After a tragedy occurs at the school, a mysterious fainting epidemic breaks out threatening the stability of all involved.
35. The Constant Gardener (2005)
R | 129 min | Drama, Mystery, Romance
A widower is determined to get to the bottom of a potentially explosive secret involving his wife's murder, big business, and corporate corruption.
Votes: 126,770 | Gross: $33.58M
36. Outbreak (1995)
R | 127 min | Action, Drama, Thriller
Army doctors struggle to find a cure for a deadly virus spreading throughout a California town that was brought to America by an African monkey.
Votes: 102,198 | Gross: $67.82M
37. Ravenous (2017)
TV-MA | 104 min | Drama, Horror, Sci-Fi
In a small, remote village in northern Quebec, things have changed. Locals are not the same anymore - their bodies are breaking down and they have turned against their loved ones. A handful of survivors goes hiding in the woods, looking for others like them.
38. The Omega Man (1971)
PG | 98 min | Action, Drama, Sci-Fi
Lone survivor, doctor Robert Neville, struggles to create a cure for the plague that wiped out most of the human race while fighting The Family, a savage luddite death cult formed by the zombie-like infected to erase the past.
Votes: 27,057 | Gross: $8.72M
39. Equals (2015)
PG-13 | 101 min | Drama, Romance, Sci-Fi
In an emotionless utopia, two people fall in love when they regain their feelings from a mysterious disease, causing tensions between them and their society.
Votes: 24,873 | Gross: $0.03M
40. Sahara (2005)
PG-13 | 124 min | Action, Adventure, Comedy
Master explorer Dirk Pitt goes on the adventure of a lifetime of seeking out a lost Civil War battleship known as the "Ship of Death" in the deserts of West Africa while helping a WHO doctor being hounded by a ruthless dictator.
Votes: 87,771 | Gross: $68.67M
41. Lara Croft Tomb Raider: The Cradle of Life (2003)
PG-13 | 117 min | Action, Adventure, Fantasy
Adventurer Lara Croft goes on a quest to save the mythical Pandora's Box, before an evil scientist finds it, and recruits a former Marine turned mercenary to assist her.
Votes: 123,780 | Gross: $65.66M
42. Mimic (1997)
R | 105 min | Horror, Sci-Fi
Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.
Votes: 43,466 | Gross: $25.48M
43. Quarantine (2008)
R | 89 min | Horror, Thriller
A television reporter and her cameraman are trapped inside a building quarantined by the CDC, after the outbreak of a mysterious virus which turns humans into bloodthirsty killers.
Votes: 66,248 | Gross: $31.69M
45. The Invasion (I) (2007)
PG-13 | 99 min | Sci-Fi, Thriller
As a Washington, D.C. psychiatrist unearths the origin of an alien epidemic, she also discovers her son might be the only way it can be stopped.
Votes: 71,942 | Gross: $15.07M
46. Repo! The Genetic Opera (2008)
R | 98 min | Horror, Musical, Sci-Fi
A worldwide epidemic encourages a biotech company to launch an organ-financing program similar in nature to a standard car loan. The repossession clause is a killer, however.
Votes: 22,607 | Gross: $0.14M
49. The Last Man on Earth (1964)
Not Rated | 86 min | Drama, Horror, Sci-Fi
When a disease turns all of humanity into the living dead, the last man on earth becomes a reluctant vampire hunter.