Previously known as Jambusters, the period piece follows a group of inspirational women in Cheshire at the height of World War II.
Banding together as the Great Paxford Women's Institute, they help maintain the nation's fabric in its darkest hour.
Downton Abbey's Samantha Bond and Cranford's Francesca Annis will lead the cast, which also includes Mark Bonnar (Line of Duty), Ruth Gemmell (Utopia), and Claire Rushbrook (My Mad Fat Diary).
Mark Bazeley (The Suspicions of Mr Whicher), Frances Grey (The Widower) and Ed Stoppard (Cilla) will also feature in Simon Block's adaptation of Julie Summers's non-fiction book Jambusters.
"We're really delighted to have commissioned Home Fires," said ITV's Director of Drama Steve November. "Great writing from Simon has given Julie Summers's wonderful book a fictional life.
"The women are real and engaging