Following a harrowing escape from Roller's (Jack Kesy) grasp, Desna (Niecy Nash) is on the run. Roller is close behind, running from the Russians. Dean (Harold Perrineau), Polly (Carrie Preston) and Virginia (Karrueche ...
Desna and her girls take pride in doing nails at the Nail Artisans of Manatee County, but amidst painting hooves and dreaming of a better life, she finds herself entangled in a money laundering scheme with the Dixie Mafia. As New Year's Eve approaches, Desna's promise of getting out and going clean is complicated when things go south with Roller , leading her and newcomer Virginia to take matters into their own hands, changing their lives forever.
Following their entanglement with Roller, Desna and Virginia desperately prepare a cover story to tell the girls and the Dixie Mafia. Meanwhile, Desna's dream salon is falling out of her grasp. Virginia suddenly goes MIA, only to return with a concocted story that sends Desna on a journey she never thought she would have to take.
As Virginia's (Karrueche Tran) lies deepen, Desna (Niecy Nash) plays catch-up covering their tracks. Desna still has a small shot at her dream salon, and with the help of her crew, she is determined to get it. Something goes awry at the clinic, putting Desna and Bryce (Kevin Rankin) in danger of Uncle Daddy's (Dean Norris) wrath until they can figure a way out.
Desna and Jennifer may be Dr. Ken's only hope, as Bryce wrongly accuses him of a heinous crime. Dean sees a disturbing billboard ad that hits too close to home, leaving Desna to cope with the dark aftermath. Meanwhile, Virginia and Desna are forced to go to Polly for help to rid the world of two horrible birds from Desna's past, with one well-aimed stone.
Desna and her ladies visit the new salon for the first time. They enter the Florida premier nail design competition for cash prizes. Virginia feels left out when she's named the alternate. Jennifer finds out one of Desna's dark secrets.
After the big nail competition, Desna (Niecy Nash) may finally get out from Uncle Daddy's (Dean Norris) grasp. Jennifer (Jenn Lyon) struggles knowing Desna's dark secret, while Polly (Carrie Preston) discovers her previously unknown maternal instincts. Meanwhile, Dean (Harold Perrineau) may have found his first feelings of romantic love and makes a discovery that threatens to destroy everyone he knows and loves.
With a shocking revelation affecting the entire crew, Jennifer (Jenn Lyon) finds unexpected solace in her square-dancing instructor, Hank (Hunter Burke). Polly (Carrie Preston) uses all of her powers of bad for good, for the first time, while Quiet Ann (Judy Reyes) is torn about a big decision. Scary times are in store for Virginia (Karrueche Tran), but for Desna (Niecy Nash) most of all.
With the clock ticking, Desna scrambles to get out of her worst trouble yet, and when her sleuthing pays off, she goes to the only person who can save her; Jennifer learns to cope as a Dixie Mafia wife.
Following a harrowing escape from Roller's (Jack Kesy) grasp, Desna (Niecy Nash) is on the run. Roller is close behind, running from the Russians. Dean (Harold Perrineau), Polly (Carrie Preston) and Virginia (Karrueche Tran) frantically search for Desna before time runs out. Meanwhile, Jennifer (Jenn Lyon) gets more deeply involved with Hank (Hunter Burke), oblivious to how close her life is to imploding. In the end, only Desna can save Jennifer, Roller, and her crew with a sacrifice greater than any she's ever had to make.