Incorrectly regarded as goofs
Correction: The pressure is important: Your eyes, if left open, would basically boil and surface freeze because of lack of pressure on the liquid. Your tongue would be susceptible as well. The pressure issue would also make it impossible to hold air in your lungs, so you would pass out within a minute, but likely much sooner: "In 1965, while performing tests at the Johnson Space Center, a subject was accidentally exposed to a near vacuum (less than 1 psi) when his space suit leaked while in a vacuum chamber.
He did not pass out for about 14 seconds, by which time unoxygenated blood had reached his brain. Technicians began to repressurize the chamber within 15 seconds and he regained consciousness at around the equivalent of 15,000 feet of altitude. He later said that his last conscious memory was of the water on his tongue beginning to boil. So, there's at least one data point about what it's like to be in a vacuum. It won't be pleasant, but it won't be like the movies, either."
However, this error can be argued by saying that he could be referencing to a past event, and not his direct cameo in Civil War. This can only be solved by relying on the possibility that if the Stan Lee cameos in all MCU films are the same person, it would have to be that the Informant would have to continuously switch jobs (he is seen as, for example, a Smithsonian Security Guard in Captain America: The Winter Soldier and a Bartender in Ant-Man) throughout the MCU timeline.