The country that Dru lives in and Gru originates from is the fictional European country of Freedonia. This is the same name as a similar fictional European country in the Marx brothers' movie Duck Soup (1933).
In one scene in Gru's lair the Minions are standing in front of a big computer machine with a green screen. The screen is actually displaying the Page R (the music sequencer screen) from a Fairlight CMI synthesiser series II which cost around £30,000 when originally launched back in 1982. It is unclear from the brief appearance in the movie what is being played back on the screen.
This film will feature Balthazar Bratt as the new villain. Other villains in the Despicable Me franchise have been Vector, El Macho, and Scarlet Overkill. Voiced by Jason Segel, Benjamin Bratt, and Sandra Bullock respectively.
The army of Bratt dolls that Balthazar Bratt sends to kill Gru are referred to as 'the Bratt pack' this is a clear reference to the name given by the media, to a group of 80s actors, popular for films such as ' The Breakfast Club' and 'St Elmo's Fire'.